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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP4
All Species:
23.03
Human Site:
S1875
Identified Species:
56.3
UniProt:
O75096
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75096
NP_002325.2
1905
212045
S1875
E
E
Q
S
E
C
S
S
V
H
T
A
A
T
P
Chimpanzee
Pan troglodytes
XP_508403
2080
230042
S2050
E
E
Q
S
E
C
S
S
V
H
T
A
A
T
P
Rhesus Macaque
Macaca mulatta
XP_001111133
1905
212150
S1875
E
E
Q
S
E
C
S
S
V
H
T
A
A
T
P
Dog
Lupus familis
XP_540748
2021
223644
S1991
E
E
Q
S
E
C
S
S
V
H
T
A
A
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI56
1905
211935
S1875
E
E
Q
S
E
C
S
S
V
H
T
A
A
T
P
Rat
Rattus norvegicus
Q9QYP1
1905
211861
S1875
E
E
Q
S
E
C
S
S
V
H
T
A
T
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519450
1486
165094
A1457
T
G
R
N
T
I
E
A
A
R
L
D
G
S
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Q99087
909
101277
T879
D
N
P
V
Y
Q
K
T
T
E
E
D
Q
V
H
Zebra Danio
Brachydanio rerio
XP_002663079
1882
210459
E1852
Q
E
G
D
H
Q
S
E
C
S
S
I
S
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P98163
1984
219502
P1951
R
G
V
G
R
Q
V
P
D
I
L
V
A
D
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
99.1
92.3
N.A.
96.8
96.6
N.A.
73.2
N.A.
22.3
77.7
N.A.
23
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.5
93.4
N.A.
98.3
98.3
N.A.
75.2
N.A.
31.3
86.8
N.A.
40.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
N.A.
0
20
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
26.6
N.A.
13.3
40
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
60
60
0
0
% A
% Cys:
0
0
0
0
0
60
0
0
10
0
0
0
0
0
10
% C
% Asp:
10
0
0
10
0
0
0
0
10
0
0
20
0
10
0
% D
% Glu:
60
70
0
0
60
0
10
10
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
10
10
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
60
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
60
% P
% Gln:
10
0
60
0
0
30
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
10
0
10
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
60
0
0
70
60
0
10
10
0
10
10
0
% S
% Thr:
10
0
0
0
10
0
0
10
10
0
60
0
10
70
10
% T
% Val:
0
0
10
10
0
0
10
0
60
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _